Medicine · 3rd year — UE 1
Teaching unit 1 · Synthetic summary

Psychology,
Semiology
& Pathophysiology

Cardiovascular and respiratory systems — the essentials of the condensed module for 3rd year students.

Medical psychology General semiology Cardiovascular Respiratory Radiology Pathophysiology Biochemistry
1

Medical psychology

The care relationship, communication and the experience of illness

Medical psychology studies the human and relational dimension of care: how the patient experiences their illness, and how the doctor establishes a quality therapeutic relationship.

Doctor–patient relationship & communication

The clinical encounter is based on a verbal and non-verbal communication. The doctor must practiceactive listening, theempathy (understanding the feeling without replacing it) and the absence of judgment. The quality of this alliance determines the compliance and effectiveness of the treatment.

Announcement of a serious illness

The announcement is a structured act (standard protocol SPIKES): choose a quiet place, assess what the patient knows, ask them what they want to know, deliver the information in stages, welcome their emotions, then define a care plan. Lying is prohibited, but information is progressive and adapted.

Stress & psychosomatic disorders

The stress is an adaptation response (general Selye adaptation syndrome: alarm → resistance → exhaustion) with axis friendly (adrenaline) and axis corticotrope (cortisol). Chronic stress promotes so-called psychosomatic disorders (hypertension, ulcer, asthma, eczema, etc.) where the psyche affects the body.

Personality functioning & pain

Things to remember

Empathy, active listening and shared decision-making are at the heart of the care relationship. Delivering bad news follows a protocol. Chronic stress has a neurohormonal substrate (cortisol/adrenaline) and pain is both a physical and psychological experience.

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2

General semiology

Medical language, clinical examination and reasoning

Semiology is the science of signs: collecting, describing and grouping symptoms and signs to arrive at a diagnosis.

Basic vocabulary

TermDefinition
SymptomDisorder felt and reported by the patient (subjective) — e.g. pain.
SignObjective manifestation noted by the doctor — e.g. fever, breath.
SyndromeSet of signs/symptoms occurring together.
DiagnosisDisease identification from data.
PredictionPredictable course of the disease.

The clinical examination

It always takes place in the same rigorous order:

  1. Interrogation (history): marital status, reason, history of illness, personal and family history, lifestyle.
  2. Inspection: naked eye observation.
  3. Palpation: exploration through touch.
  4. Percussion: sounds obtained by striking (dull / sonorous / tympanic).
  5. Auscultation: listen with a stethoscope.

The whole thing is recorded in themedical observation, structured written document.

Clinical reasoning

Hypothetico-deductive approach: from the signs, we build diagnostic hypotheses (differential diagnoses), confirmed or ruled out by additional targeted examinations.

Weight semiology

BMI = weight (kg) / height² (m). Weight loss < 18.5; normal 18.5–25; overweight 25–30; obesity > 30. We analyze weight loss and weight gain according to their speed and their cause.

Temperature (fever)

Fever = temperature > 38°C. We specify type (continuous, remitting, intermittent), duration and associated signs. Hypothermia < 35°C is also pathological.

Hydro-electrolyte balance

Things to remember

Distinguish between symptom/sign/syndrome. The clinical examination always follows the order inspection → palpation → percussion → auscultation, preceded by questioning. Everything ends with a written medical observation.

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3

Cardiovascular semiology

From symptom to heart syndrome

Recognize the signs of the heart and vessels, then group them into major syndromes (hypertension, angina, heart attack, heart failure, etc.).

Functional signs (what the patient feels)

Physical examination of the heart

Inspection and palpation of peak shock (5ᵉ left intercostal space), then auscultation of the 4 foci (aortic, pulmonary, tricuspid, mitral):

Peripheral examination

Taking pulse (regularity, symmetry), measurement of blood pressure, looking for edema, jugular turgor and hepatojugular reflux.

Explorations

ReviewIntake
ECGRhythm, conduction, ischemia (ST elevation/depression), hypertrophies.
Chest x-rayCardiomegaly (cardiothoracic index > 0.5), pulmonary overload.
Cardiac Doppler ultrasoundVentricular function (LVEF), valves, pericardium.
BiologyTroponin (myocardial necrosis), BNP/NT-proBNP (heart failure), lipid profile.

Major cardiovascular syndromes

HTA

BP ≥ 140/90 mmHg. Often silent; major risk factor for stroke, MI and kidney failure.

Angina / ACS

Myocardial ischemia due to coronary insufficiency. The acute coronary syndrome includes unstable angina and infarction (with or without ST elevation).

Myocardial infarction

Myocardial necrosis: prolonged pain, ST elevation, troponin elevation.

Pericarditis

Inflammation of the pericardium: pain increased on inspiration and calmed when leaning forward, pericardial friction, diffuse concave ST elevation.

Valvulopathies

Narrowing (stenosis) or leaking (insufficiency) of the mitral and aortic valves → characteristic murmurs.

OAP

Acute pulmonary edema: respiratory distress, crackles, foamy expectoration — left heart failure emergency.

Vascular semiology

Things to remember

Five key functional signs: chest pain, dyspnea (NYHA), palpitations, syncope, claudication. B1/B2 and murmurs on auscultation. Troponin = heart attack, BNP = heart failure.

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4

Respiratory semiology

Signs, syndromes and investigations of the pulmonary system

The respiratory system is explored through functional and physical signs, grouped into major pleuropulmonary syndromes.

Functional signs

Physical signs (the 4 times)

TimeSearch
InspectionRespiratory rate, drawing, cyanosis, chest deformities.
PalpationVocal vibrations (increased if condensation, decreased if effusion).
PercussionDullness (fluid/condensation) or tympanism (pneumothorax).
AuscultationVesicular murmur, rattles (crackles, snoring, sibilants), tubal murmur.

Major syndromes

Pulmonary condensation

Dullness, increased vocal vibrations, tubal murmur, crackles (e.g. pneumonia).

Pleural fluid effusion

Dullness, abolition of gallbladder murmur and vocal vibrations (pleurisy).

Gaseous effusion (pneumothorax)

Tympanism, auscultatory silence, abolition of vocal vibrations.

Bronchial syndrome

Snoring and wheezing rales, productive cough (bronchitis, asthma).

Interstitial syndrome

Dry “Velcro” crackles, exertional dyspnea (fibrosis, edema).

Mediastinal syndrome

Compression: dysphonia, dysphagia, superior cava syndrome.

Explorations

Things to remember

The coupling vocal vibrations + percussion + auscultation directs the syndrome: condensation (dullness + increased VV) ≠ fluid effusion (dullness + abolished VV) ≠ pneumothorax (tympanism + abolished VV).

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5

Radiology & imaging

Physical principles and radiological semiology

Medical imaging is based on four main techniques with distinct physical principles; each has its own indications.

TechnicalPrincipleSpecial features
X-rayX-rays passing through tissues (densities).Radiant. 4 densities: air (black), fat, water/tissue, bone/calcium, metal (white).
UltrasoundReflected ultrasound (echoes).Non-irradiating, real time; hampered by air and bone.
CT (scanner)X-rays + sectional reconstruction.Very radiant, high resolution.
IRMMagnetic field + radio frequencies (H protons).Non-irradiating, excellent for soft tissues.

Contrast products

They increase the contrast: iodized (scanner, radio) and gadolinium (MRI). Beware of contraindications (allergy, renal insufficiency).

Chest imaging

The frontal chest x-ray (standing, inhaling) is the basis. The big ones thoracic radiological syndromes : alveolar, interstitial, pleural, mediastinal, bronchial. The silhouette sign locates an opacity according to the disappearance of a cardiac or diaphragmatic edge.

Cardiovascular imaging

Analysis of the cardiac silhouette (cardio-thoracic index), large vessels, and dedicated explorations: echocardiography, CT angiography, cardiac MRI.

Things to remember

Know the 4 radiological densities and know which technique to choose: bone/lung → radio/CT, soft tissues → MRI, abdomen/heart in real time → ultrasound.

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6

Pathophysiology

Mechanisms of major failures

Understand the mechanisms that cause the transition from normal to pathological: hydro-electrolyte balance, heart failure, shock and respiratory failure.

General pathophysiology

Cardiovascular pathophysiology

Heart failure: inability of the heart to provide sufficient flow. Cardiac output depends on the preload, from the afterload, from the contractility and frequency (Frank-Starling law). Compensatory mechanisms: tachycardia, dilatation/hypertrophy, neurohormonal activation.

States of shock

Acute circulatory failure → tissue hypoperfusion and cellular suffering.

TypeMechanism
HypovolemicDecrease in blood volume (hemorrhage, dehydration).
CardiogenicHeart pump failure (massive MI).
SepticVasodilation and capillary leak of infectious origin.
AnaphylacticVasoplegia of allergic origin (histamine release).

HTA : elevation of BP by increase in peripheral resistance and/or flow, with role of the renin-angiotensin system.

Respiratory pathophysiology

Things to remember

Cardiac output = preload × contractility × rate / afterload. The 4 shocks: hypovolemic, cardiogenic, septic, anaphylactic. AKI = hematosis defect; Virchow's triad explains thrombosis.

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Clinical biochemistry

Cardiovascular and respiratory biological markers

Biochemistry provides the markers that confirm and track unit pathologies.

Introduction

The notion of“healthy man” defines the reference values. Any analysis goes through three phases: pre-analytical (withdrawal), analytical (dosage), post-analytical (interpretation).

Cardiovascular biochemistry

Respiratory biochemistry

The analysis of puncture fluids (pleural) distinguishes transudate (hydrostatic mechanism, poor in proteins) and exudate (inflammatory mechanism, rich in proteins) according to Light's criteria.

Things to remember

Troponin = heart attack; BNP = heart failure; LDL = atherosclerotic risk. Pleural fluid: transudate (hydrostatic) vs exudate (inflammatory).

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Educational summary of UE1 — summary produced from the official 3rd year medical program (Psychology, general semiology, cardiovascular and respiratory system). Revision document: it does not replace detailed lessons and teacher handouts.

Program source: univ.ency-education.com — 3rd year course, Unit 1.

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